
Mesalazine
Mesalazine works by reducing inflammation of the large intestine (colon and rectum) and therefore improves symptoms related to ulcerative proctitis and colitis. There are many different preparations and brands of mesalazine (Salofalk, Asacol, Pentasa, Mezavant, Colazide, Ipocol, Mesren). Some brands have proven advantages in certain patients but overall they are similar. I tend to recommend Salofalk granules first-line because of once daily dosing.